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John J. Dennehy
Position: Professor, Biology
Campus Affiliation: Graduate Center|Queens College
Phone: (718) 997-3411
Degrees/Diplomas: Ph.D. in Biology from Clark University
M.S. in Zoology from University of Idaho
Subprogram: Molecular, Cellular, and Developmental Biology|Ecology, Evolutionary Biology, and Behavior
Research Interests: Viruses, bacteriophages, gene expression control, cellular event timing, mathematical modeling, virus molecular biology, virus evolution and ecology, systems biology
Research Focus: Microorganisms|Evolution|Molecular Biology, Genomics And Biochemistry|Cellular/Molecular|Ecology1|Immunology/Infectious Disease|Biochemistry/Protein Structure
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John Dennehy is a virologist who is interested in all aspects of virus biology ranging from virus molecular biology to virus ecology and evolution. Dr. Dennehy earned a Ph.D. at Clark University and was a postdoctoral fellow at Yale University and the State University of New York At Albany prior to joining the faculty at Queens College in 2007. Research in the Dennehy Laboratory employs bacteriophages, rotaviruses, and coronaviruses as model organisms to test predictions generated by theory and mathematical modeling. We probe how viruses evolve at the molecular level to best exploit host cells and propagate in host populations. Additionally, we explore gene expression regulatory mechanisms to determine how processes such as virus infection, assembly, and life history event timing are controlled. Other topics of interest include the biology of virus collective infection via extracellular vesicles, virus coevolution and exploitation of hosts, phage therapy, and virus systems biology. Dr. Dennehy has published over 50 articles, book chapters and conference papers on virus biology. He is also a Senior Editor for Microbiology Resource Announcements, an Associate Editor for Virus Evolution, and a Curator for the American Society of Microbiology’s COVID-19 Research Registry. 

Awards and Grants
  • Phylodynamics and Evolution of SARS-CoV-2 in NYC (NYC Department of Environmental Protection)
  • Metapopulation Modeling to Develop Strategies to Reduce COVID-19 Transmission in Public Spaces (National Science Foundation)
  • Novel Strategies for Treating Biofilm-Forming Pathogens with Phage Therapy (National Institutes of Health)
  • Consequences and Control of Randomness in the Timing of Intracellular Events (National Institutes of Health)
Professional Affiliations and Memberships
  • American Society for Microbiology
  • American Society of Naturalists
  • American Society for Virology
  • Society for the Study of Evolution
  • World Society for Virology
Courses Taught
  • General Microbiology
  • Ecology and Evolution of Infectious Diseases
  • Evolution
  • Phage Hunters
Publications