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Courses

The doctoral courses are divided into two levels: those numbered 70000 are rrequired core courses and those numbered 80000 are advanced, special topics courses and seminars. Typically students complete the core courses and two semesters of seminars during their first year (30 credits).

Unless otherwise stated, all courses are 45 hours, 3 credits.

Biochemistry Program Core Courses (All required except for BICM 71130).

BICM 71010 - Advanced Biochemistry I (Protein Structure and Function/Metabolism)
Protein structure, enzyme kinetics, binding proteins, allostery; metabolism of carbohydrates, lipids, amino acids, and nucleotides; physiological relevance and regulation of pathways.
Prerequisite: A one semester course in biochemistry

BICM 71020 - Advanced Biochemistry II (Bioenergetics/Molecular Biology)
Membranes: structure, transport and other functions; muscle and cytoskeletal biochemistry; bioenergetics: respiration and photosynthesis; DNA replcation, transcription, translation; RNAs; genetic technologies.
Prerequisite: A one semester course in biochemistry

BICM 71110 - Research Techniques in Biochemistry I
2-6 credits
Students perform rotations in 3 or 4 laboratories to gain experience in modern research techniques.
Corequisite: BICM 71010

BICM 71120 - Research Techniques in Biochemistry II 
2-6 credits
Continuation of Biochemistry 71110
Prerequisite: BICM 71110

BICM 71130 - Research in Biochemistry
2-6 credits
Continuation of Biochemistry 71120 when necessary.
Prerequisites: BICM 71110 and BICM 71120

BICM 72010 - Basic Seminar in Biochemistry I
1 credit
In-depth analysis of topics covered in BICM 71010 using current literature.  Students prepare individual or group presentations.

BICM 72020 - Basic Seminar in Biochemistry II
1 credit
In-depth analysis of topics covered in BICM 71020 using current literature.

BICM 75000 - Bioorganic Chemistry
Structural and physical chemistry of molecules relevant to biological systems including drugs; interactions between ligands and macromolecules such as drugs and their targets; molecular design.

BICM 77000 – Physical Biochemistry
Principles and applications of classical and statistical thermodynamics, spectroscopy, kinetics, x-ray crystallography and other techniques to the study of biochemical systems.

Advanced Courses

BICM 81000 – Seminar in Biochemistry
15 hours, 1 credit
Must be taken three semesters; usually designed around relevant current literature and with visiting scientist presentations.

BICM 82000 – Doctoral Disseratation Research
Credits variable
Prerequisite: Successful performance on the First Level Examination

BICM 84000 - Enzymology
Enzyme structure; specialized kinetics; mechanisms in detail; active site design; regulation of catalytic activity; drugs as inhibitors.

BICM 85000 - Nucleic Acid Metabolism and Function
Current views on the molecular structure of DNA and RNA, their biosynthesis and degradation, their functional role in protein synthesis and in development.

BICM 87000 - Bioinformatics
The use of databases for comparative analysis of biomolecules and their functions; visualization and evolutionary and homology relationships among macromolecular sequences and structures.

BICM 88800 – Current Topics in Biochemistry
15 hours, 1 credit
Recent advances in selected areas of biochemistry.

BICM 90000 – Dissertation Supervision
1 credit, repeated each semester until degree is completed.
 Prerequisite: Completion of all required courses.