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The pop-culture universe of superheroes is filled with extraordinary humans and abilities. Captain America, the Hulk, and Black Panther seem to lie firmly in the realm of fantasy, but the technology behind them might not be as farfetched as we think. In his book The Science of Marvel, Sebastian Alvarado shows that, using quantum physics, evolutionary biology, and mechanical engineering, we can find real-world parallels to superpowers such as “spidey sense” and Thor’s lightning. He speaks with Shane Campbell-Staton, host of the podcast The Biology of Superheroes, about where the science meets the fiction. Alvarado is an assistant professor of biology at Queens College and The Graduate Center, CUNY; Stanton is an assistant professor of biology at UCLA.