Application of an interdisciplinary evolutionary biology perspective to the epidemiology and etiology of complex chronic diseases. Key insights include:
Androgens may cause ischemic heart disease (IHD) and protect against diabetes, explaining men’s higher rates of IHD, and suggests contextually specific differences in disease patterns may be driven by environmental influences on androgens
Statins lower androgens, explaining why statins are more effective than other lipid-modulating therapies.
Inflammation may partially be a symptom of the higher levels of androgens causing IHD, because androgens trade-off against immunity, thus explaining why inflammatory markers predict, but may not cause, IHD.
Note: This list is generated by an automated search in the database PubMed. Due to the automated nature of the search, the list may not be comprehensive and may contain inaccuracies.